منابع مشابه
Biological Timekeeping.
The daily transition from light to darkness has significantly shaped the evolution of most living species, from unicellular organisms to mammals. Adaptation to this environmental constraint occurred through the emergence of a circadian system capable of adjusting both behavioral and physiological processes to this light-dark cycle. Superimposed upon the daily light-dark cycle is a seasonal infl...
متن کاملBiological timekeeping in the presence of stochasticity
Causal ordering of key events in the cell cycle is essential for proper functioning of an organism. Yet, it remains a mystery how a specific temporal program of events is maintained despite ineluctable stochasticity in the biochemical dynamics which dictate timing of cellular events. We propose that if a change of cell fate is triggered by the time-integral of the underlying stochastic biochemi...
متن کاملInternet Timekeeping Around the Globe
This paper describes a massive survey of Network Time Protocol @TI") servers and clients in order to discover statistics of time and frequency mm, as well as determine the health and welfare of the NTP synchronization subnet operating in the global Internet. Among the conclusions of the survey are that most NTP clocks are within 21 ms of their synchronization sources and all are within 29 ms on...
متن کاملTimekeeping in VMware Virtual Machines
Because virtual machines work by time‐sharing host physical hardware, a virtual machine cannot exactly duplicate the timing behavior of a physical machine. VMware virtual machines use several techniques to minimize and conceal differences in timing behavior, but the differences can still sometimes cause timekeeping inaccuracies and other problems in software running in a virtual machine. This i...
متن کاملCircadian timekeeping and output mechanisms in animals.
Daily rhythms in animal behavior, physiology and metabolism are driven by cell-autonomous clocks that are synchronized by environmental cycles, but maintain ∼24 hours rhythms even in the absence of environmental cues. These clocks keep time and control overt rhythms via interlocked transcriptional feedback loops, making it imperative to define the mechanisms that drive rhythmic transcription wi...
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ژورنال
عنوان ژورنال: Sleep Medicine Clinics
سال: 2009
ISSN: 1556-407X
DOI: 10.1016/j.jsmc.2009.01.005